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Provigil/ Modafinil

Printed From: www.msdiscuss.com
Category: Multiple Sclerosis Discussion Forum
Forum Name: Treatments, Therapies and Alternative Medicine
Forum Discription: Discuss the safety, benefits and cost effectiveness of various treatments, therapies and potential complementary and alternative medicines for MS.
URL: http://www.msdiscuss.com/forum_posts.asp?TID=60
Printed Date: 09 Feb 2010 at 2:49am


Topic: Provigil/ Modafinil
Posted By: Tracey Lynn
Subject: Provigil/ Modafinil
Date Posted: 16 Nov 2006 at 11:36am
Hello everybody!
 
I was diagnosed with relapsing/ remitting MS just over 2 years ago.  I take 2 Provigil/ Modafinil pills daily for my fatigue.
 
I deal with the usual MS fatigue and find the Provigil does help because on the days when I don't (or forget to) take the pills I'm really tired and have a very hard time focusing, concentrating, and thinking.  But recently I've been having to drink coffee for a little caffeine "boost" at work in the afternoons.
 
I've been playing with when I take my Provigil pills.  Some days I take 1 pill first thing in the morning then my other pill around lunchtime; some days I take both pills together at the same time in the morning. 
 
Does anybody else here take Modafinil for your fatigue?  When do you feel it is more effective to take them? 
 
Thanks for any advice!


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TLC
"I will get by; I will survive" - the Grateful Dead

=^..^=


Replies:
Posted By: Michelle23
Date Posted: 05 Oct 2007 at 4:55pm
hello
 
what kind of pills are they,  they did you get them from the store or pharmacy or did you dr. recomment them?

Posted By: Miyoko
Date Posted: 16 Nov 2007 at 7:43pm
modafinil (Provigil) : is a wakefulness-promoting agent.  I found two papers discussing the outcome of their clinical trials..with somewhat conflicting results.
1) Study by Ohio State University
     They found 200 mg/day modafinil significantly improved fatigue and was well tolerated by MS patients.
2) Study by Hopital de la Salpetriere (France)
     Starting with 200 mg/day of modafinil:  found NO improvement of fatigue in MS pateints judged by the Modified Fatigue Impact Scale.
If you want to try this drug, you should speak to your doctor.  Maybe it will work well for you.

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Miyoko


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